- Neurology / David Geffen School Of Medicin / UCLA
Position overview
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Application Window
Open date: June 28, 2023
Next review date: Friday, Jul 28, 2023 at 11:59pm (Pacific Time)
Apply by this date to ensure full consideration by the committee.
Final date: Friday, Jul 28, 2023 at 11:59pm (Pacific Time)
Applications will continue to be accepted until this date, but those received after the review date will only be considered if the position has not yet been filled.
Position description
Assistant Project Scientist
Alzheimer Laboratory
Position Description
We seek an experienced scientist to advance our research at the University of California, Los Angeles Department of Neurology in the laboratory of Dr. Rexach.
Dr. Rexach’s laboratory studies Alzheimer’s and related dementias. Our research focuses on genetic mechanisms of disease as well as interventions with primary focus on neuroimmune mechanisms and resilience factors contributing to neurodegeneration. We conduct studies in iPSC-derived stem cell models that allow us to model disease and disease modifying factors. The successful candidate will be responsible for supervising graduate students, post-doctoral fellows, and undergraduate student researchers, preparing manuscripts for publication in scientific journals, and assisting with the preparation of grant proposals.
Specific Responsibilities
Responsibilities of this position include study design, data acquisition, statistical computation, and literature review and manuscript/grant preparation. This includes ability to work with the PI to develop and utilize a host of iPSC models if dementia, and work closely with senior faculty and the PI supervising teams of technicians and students to complete the multidisciplinary tasks involved in each study (iPSC culturing, quality controls, single cell sequencing, phenotyping, genetic and pharmacological manipulation, functional readouts including electrophysiology). The project scientist should also have experience with neuron and/or glial cell culture in to study neurotoxicity, aggregation or inflammatory responses . The scientist is expected to submit at least one career training grant by the end of the first year and assist in grant preparation as a co-investigator by the end of the first year.
Qualifications
Applicants must have a PhD and postdoctoral fellowship. Ideal candidates will have a strong background in the following areas: protein aggregation pathologies, different types of dementia (tau, Alzheimer’s, mixed), iPSC models, genetic manipulation, and data analysis.
Applicants must have experience with the use of flow cytometry, immunohistochemical, iPSC culturing, gene induction and knockdown with CRISPR and viral vectors and statistics. Prior experience with preclinical models of neurodegeneration is preferred.
Additional Duties
• Ability to work on multiple projects efficiently and effectively.• Ability to work independently on scientific projects• Required to communicate well with other scientists.• Candidate should have 5 years research experience in neuroscience in an academic setting or equivalent. • The candidate will report directly to the Principal Investigator and will successfully carry out experiments and analyze the data generated with minimal supervision.
Document requirements
Curriculum Vitae (updated)
Bibliography
Statement of Research
Statement on Contributions to Equity, Diversity, and Inclusion
Cover Letter (Optional)
Three references (Optional)
Application procedure: Apply by submitting your application to our online RECRUIT system at https://recruit.apo.ucla.edu/JPF08571 along with CV, statement of research, and 3 references (optional). Screening of applicants will begin immediately and will continue until the position is filled.
Please be advised that the final candidate recommended for hire into a critical (or otherwise designated) position will be required to successfully complete a background investigation. Any convictions will be evaluated to determine if they directly relate to the responsibilities and requirements of the position. Having a conviction history will not automatically disqualify an applicant from being considered for employment.
The offer of this position is contingent on the successful completion of a background check prior to your first day of employment and evidence of authorization to work in the United States. Also by accepting this offer you are acknowledging compliance with UCLA Health policy by receiving your influenza vaccination prior to your start date. If you are in agreement with the terms and conditions of this offer, please sign and return the enclosed copy of this letter. Feel free to contact Davis D. del Pino at 310-206-6567 to discuss any questions you may have regarding employment.
As a condition of employment, you will be required to comply with the University of California Policy on Vaccination Programs – With Updated Interim Amendments. All Covered Individuals under the policy must provide proof of receiving the COVID-19 Vaccine Primary Series or, if applicable, submit a request for Exception (based on Medical Exemption, Disability, Religious Objection, and/or Deferral based on pregnancy or recent COVID-19 diagnosis and/or treatment) no later than the applicable deadline. All Covered Individuals must also provide proof of receiving the most recent CDC-recommended COVID-19 booster or properly decline such booster no later than the applicable deadline. New University of California employees should refer to Exhibit 2, Section II.C. of the SARS-CoV-2 (COVID-19) Vaccination Program Attachment for applicable deadlines. All Covered Individuals must also provide proof of being Up-To-Date on seasonal influenza vaccination or properly decline such vaccination no later than the applicable deadline. Please refer to the Seasonal Influenza Vaccination Program Attachment. (Capitalized terms in this paragraph are defined in the policy.) Federal, state, or local public health directives may impose additional requirements.
The University of California is an Equal Opportunity/Affirmative Action Employer advancing inclusive excellence. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected categories covered by the UC nondiscrimination policy. UC Nondiscrimination & Affirmative Action Policy
UCLA is a Tobacco-Free environment. For more information, please view the policy at Tobacco-Free Campus Policy
Department: https://www.uclahealth.org/departments/neurology
Qualifications
Ph.D. degree
Application Requirements
Curriculum Vitae - Your most recently updated C.V.
Cover Letter (Optional)
Statement of Research (Optional)
Statement of Teaching (Optional)
Statement on Contributions to Equity, Diversity, and Inclusion - An EDI Statement describes a faculty candidate’s past, present, and future (planned) contributions to equity, diversity, and inclusion. To learn more about how UCLA thinks about contributions to equity, diversity, and inclusion, please review our EDI Statement FAQ document.
Reference check authorization release form - Complete and upload the reference check authorization release form
Bibliography
N/A
Help contact: ddelpino@mednet.ucla.edu
Campus Information
As a condition of employment, you will be required to comply with the University of California Policy on Vaccination Programs – With Updated Interim Amendments. All Covered Individuals under the policy must provide proof of receiving the COVID-19 Vaccine Primary Series or, if applicable, submit a request for Exception (based on Medical Exemption, Disability, Religious Objection, and/or Deferral based on pregnancy or recent COVID-19 diagnosis and/or treatment) no later than the applicable deadline. All Covered Individuals must also provide proof of receiving the most recent CDC-recommended COVID-19 booster or properly decline such booster no later than the applicable deadline. New University of California employees should refer to Exhibit 2, Section II.C. of the SARS-CoV-2 (COVID-19) Vaccination Program Attachment for applicable deadlines. All Covered Individuals must also provide proof of being Up-To-Date on seasonal influenza vaccination or properly decline such vaccination no later than the applicable deadline. Please refer to the Seasonal Influenza Vaccination Program Attachment. (Capitalized terms in this paragraph are defined in the policy.) Federal, state, or local public health directives may impose additional requirements.
The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status. For the complete University of California nondiscrimination and affirmative action policy, see: UC Nondiscrimination & Affirmative Action Policy.